Antidiabetic effects of bitter gourd extracts in insulin-resistant db/db mice
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چکیده
منابع مشابه
Genetic Divergence in Bitter Gourd
The genetic divergence among 36 genotypes of bitter gourd (Momordica charantia L.) was determined through PCA, PCO, CVA, Cluster analysis (CLSA) and Mohalanobis’s D analysis. Through multivariate analysis based on 22 characters 36 genotypes were grouped into six distant clusters. Cluster VI includes maximum genotypes (12) followed by cluster I (6) and cluster II (6). Cluster V, cluster III and ...
متن کاملBitter gourd (Momordica Charantia): A dietary approach to hyperglycemia.
Bitter gourd (Momordica charantia) is a vegetable with pantropical distribution. It contains substances with antidiabetic properties such as charantin, vicine, and polypeptide-p, as well as other unspecific bioactive components such as antioxidants. Metabolic and hypoglycemic effects of bitter gourd extracts have been demonstrated in cell culture, animal, and human studies. The mechanism of act...
متن کاملEffect of wild bitter gourd treatment on inflammatory responses in BALB/c mice with sepsis
Background/Introduction: Wild bitter gourd (Momordica charantia L. var. abbreviate Seringe) common vegetable in Asia, is used in traditional medicine to treat various diseases, including inflammation. Extant literature indicates that wild bitter gourds have components that activate PPARα and PPARγ. This research probed influence of adding wild bitter gourd to diets on inflammation responses in ...
متن کاملInheritance of gynoecism in bitter gourd (Momordica charantia L.).
The inheritance of sex expression in cucumber (Cucumis sativus) and other cucurbits is well documented; however, the genetics of female sex (gynoecism) expression in bitter gourd (Momordica charantia) has not been described. Inheritance of gynoecism in bitter gourd was studied in a 100% gynoecious line (Gy263B). The F(2) and testcross segregation data revealed that gynoecism in Gy263B is under ...
متن کاملRole of GLP-1 in the Hypoglycemic Effects of Wild Bitter Gourd
This study aimed to examine the role of GLP-1 in the hypoglycemic activity of wild bitter gourd (Momordica charantia L., BG). In vitro, the GLP-1 secretion in STC-1, a murine enteroendocrine cell line, was dose dependently stimulated by water extract (WE), its fractions (WEL, >3 kD and WES, <3 kD), and a bitter compounds-rich fraction of BG. These stimulations were partially inhibited by proben...
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ژورنال
عنوان ژورنال: British Journal of Nutrition
سال: 2010
ISSN: 0007-1145,1475-2662
DOI: 10.1017/s0007114510002680